For peanut intake, an acute trial conducted in men with overweight/obesity (n = 65) who consumed a test meal of a shake containing conventional peanuts, high-oleic peanuts, or a control biscuit showed a quicker return of insulin to basal concentrations after consumption of the shakes containing conventional peanuts and high-oleic peanuts [25]. This evidence concerns the gene INS and obesity due to melanocortin 4 receptor deficiency.