In order to prove the applicability of this technique in the absence of clear exosome markers, this study used the constrained random phage display library (CX7C) to perform multi-cycle phage screening in wild-type isogeneic tumor-bearing mice induced by the tumor cells of Eμ-myc tumor-bearing mice, and finally obtained a phage clone (Φ8) with a high affinity for the target tumor, and chemically modified the FITC on the surface of phage Φ8, so that the method has the characteristics of visualization. The gene discussed is MYC; the disease is neoplasm.