HPGDS and Parkinson disease: After four weeks of treatment, the locomotor activity of the fish was measured and brain and intestine tissues were further analyzed, in terms of peptides content, lipid peroxidation (LPO), nitric oxide (NO), alkaline phosphatase, superoxide dismutase, glutathione S-transferase (GST), acetylcholinesterase, and the expressions of PD-related genes.