CDH1 and cancer: EMT dynamics could mediate its biological impact on tumor metastasis by inhibiting the expression of epithelial markers (e.g., E-cadherin) and upregulating the expression of mesenchymal markers (e.g., Vimentin and Snail), thereby remolding the cytoskeleton and cell membrane, endowing cancer cells with increased motility and invasiveness, and causing the metastasis and spread of lesions [21].