In 2015, using rats as the model, it was found that prenatal CAF ingestion could induce DNA hypermethylation in scavenger receptor class B type I (SR-BI) promoter and inhibit SR-BI expression in fetal adrenal gland, which subsequently suppressed the cholesterol uptake, followed by decreasing the production of steroid hormones and thus increasing IUGR rates [19]. Here, SCARB1 is linked to fetal growth restriction.