when co-cultured with an endophytic fungus Epicoccum sp., and compound 13 showed moderate in vitro cytotoxic activities toward human cancer cell lines (HL-60, A549, MCF-7, SMMC-7721, and SW480) with IC50 values ranging from 15.80 to 23.03 μM and weak inhibitory activity against acetylcholinesterase (AChE) [35]. Here, ACHE is linked to cancer.