CRP and Hyperglycemia: The eigt parameters identified for the formation of the SPS were: body temperature > 38 °C, platelets (PLTs) < 150,000/mm3; decrease in feeding volume or residual > 20%; blood glucose changes > 50% (hyperglycemia or hypoglycemia); CRP > 1 mg/dL, peripheral circulation changes, estimated by capillary refill time (CRT) > 5 s, hypotension; and increase in oxygen requirements and deterioration of respiratory function (apneas, need for mechanical ventilation or changes in ventilation parameters).