Fibrinogen, as a coagulation/inflammatory biomarker strongly associated with atherogenesis [47], was correlated with Apo-B/Apo-A1, LDL-6 particles, VLDL-3 tg and VLDL-4 tg, suggesting that LPs play a prominent role in the thrombosis or inflammation process of unstable angina. This evidence concerns the gene APOB and angina unstable.