Lastly, CEC was decreased in T2DM patients using adipocytes and LpA-I (i.e., HDL particles containing apoA-I but not apoA-II) [112], Fu5AH hepatoma cells and whole plasma/serum [34,36,37,68,113,114], mouse peritoneal macrophages and isolated HDL3 [115], murine RAW264.7 macrophages and apoB-depleted serum [97], and also THP-1 macrophages and isolated HDLs [18,116]. This evidence concerns the gene APOB and type 2 diabetes mellitus.