NFKB1 and colitis: The authors considered AcEGCG as a potent anti-colitis agent due to its effects on preventing the shortening of colon length and formation of aberrant crypts, as well as lymphoid nodules in the DSS-stimulated mice, and decreasing inflammation through down-regulating of Phosphoinositide 3-kinases (PI3K)/Akt /NF-κB phosphorylation and p65 acetylation.