Among them, PC and PE were relevantly correlated with obstetric antiphospholipid syndromes (OAPS), which is characterized by the presence of circulating antiphospholipid antibodies (aPL) [38,39].These aPLs target β2—glycoprotein I (β2—GPI), a circulating blood protein with high affinity that binds to phospholipids present on the cell membrane surface, generating a chain of events that can induce thrombosis. The gene discussed is GPI; the disease is antiphospholipid syndrome.