Corinna Koebnick et al. [42] evaluated the relationships of diet, obesity, and adipokine in Mexican Americans, and indicated that in comparison to those who consumed more fruits and vegetables and less sugar-sweetened beverages, those who had a diet high in sugar-sweetened beverages had greater levels of adiposity, CRP, leptin, and MCP-1 but lower levels of SFRP-5. This evidence concerns the gene LEP and obesity due to melanocortin 4 receptor deficiency.