The deep signal pathway of the DE gene is shown for the sevoflurane and control groups in Figure 6B. The Up differentially expressed genes KEGG pathway (Figure 6C) included the IL-17 signalling pathway, malaria, osteoclast differentiation, pertussis, salmonella infection, spliceosome, ribosome, RNA transport, Alzheimer’s disease and a NOD-like receptor signalling pathway. This evidence concerns the gene IL17A and early-onset autosomal dominant Alzheimer disease.