ALB and liver dysplastic nodule: Diabetogenic agents, including streptozotocin, alloxan, a high fat diet (HFD), a fructose diet, and combinations of these ingredients, are used to induce DM in animals and establish DN conditions measured by several biomarkers, including the increase in serum urea, serum creatinine, serum uric acid, BUN, total urinary protein, and urinary albumin [22,23].