Among them we can distinguish, e.g., gelatinase (gelE, fsrA, fsrB, fsrC, sprE), adhesins (ace), aggregating substance (agg, asa1), cytolysin operon (cylA), endocarditis and biofilm-associated pili (ebpA, ebpB, ebpC), and sex pheromones (cpd, cob, ccf) [23,56]. The gene discussed is ACE; the disease is endocarditis.