The most common concomitant medications were antithrombotic agents (36.7%), beta- blockers (36.7%), agents for peptic ulcer and gastroesophageal reflux disease (33.3%), systemic corticosteroids (26.7%), oxygen (20%), expectorants (20%), and angiotensin-converting enzyme inhibitors (18.3%). This evidence concerns the gene ACE and Peptic ulcer.