SRF and cardiac hypertrophy: KLF-15 expresses in cardiomyocytes and cardiac fibroblasts and upregulates post-natally, inhibiting cardiac hypertrophy by preventing myocardin (MYOCD) and serum response factor (SRF) interactions, thus, diminishing atrial natriuretic factor (ANF) and α-skeletal actin (α-SKA) expression [34,35].