Curcumin also suppressed protein kinase B (Akt)/mammalian target of rapamycin (mTOR) phosphorylation, decreased B-cell lymphoma 2 (BCL2), and enhanced BCL-2-associated X protein (BAX) and caspase 3 cleavage, resulting in apoptosis in breast cancer cells [85]. Here, AKT1 is linked to breast cancer.