Additionally, after 2 weeks of subcutaneous low-weight heparin, the panel for thrombophilia was requested and a protein C and S deficit was found, with the other tests (lupus anticoagulant, antithrombin III, factor V Leiden, IgM and IgG antiphospholipid antibodies, IgM and IgG anti-cardiolipin antibodies, IgM and IgG anti beta-2 glycoprotein I, p-ANCA, and c-ANCA) being within normal values. The gene discussed is PRTN3; the disease is Rare hereditary thrombophilia.