CRP is a clinical marker frequently used to evaluate the presence of infection and sepsis and is frequently used in the diagnosis of intra-abdominal infections [22], as a marker of discrimination of patients with pneumonia and those with tracheal infections [23], as an aid to differentiate bacterial infection from viral and, in critical patients, elevated CRP values have been associated with increased risk of organ failure and mortality [24]. This evidence concerns the gene CRP and bacterial infectious disease.