IFNG and retinopathy of prematurity: Although IFN-γ levels in cord blood and vitreous were found to be comparable in neonates with and without ROP [23,58], one study observed that IFN-γ levels in the aqueous were significantly higher in threshold ROP eyes than in pre-threshold ROP eyes before intravitreal anti-VEGF treatment and non-ROP eyes at the time of congenital cataract extraction [204].