On the other side of the spectrum, genetic testing for predisposition to breast cancer is often considered one of the most actionable types of tests, both because the genetics of breast cancer are better understood than other areas of genetics, and because there is a range of available interventions at different levels of severity for people with a pathogenic variant in a gene such as BRCA1 or BRCA2 [10]. This evidence concerns the gene BRCA1 and breast cancer.