Recent literatures reported that resveratrol could inhibit oxidation and apoptosis in neurodegenerative diseases through the Nrf2/HO-1, SIRT1, RAX/P-PKR, and JAK2/STAT3/PI3K/AKT/mTOR signaling pathways [43,44,45,46]. The gene discussed is AKT1; the disease is neurodegenerative disease.