Utilizing a LEfSe analysis to assess differential taxa between the two breast cancer states demonstrated a significantly increased relative abundance in the following species in hormone-receptor-positive breast tissues: Order Pseudomonadales (LDA > 4), Bradyrhizobium betae, Acinetobacter johnsonii, Bradyrhizobium rifense, genus Acinetobacter, family Moraxellaceae, Undibacterium pigrum, and genus Undibacterium (LDA > 3) (Figure 5B). The gene discussed is NR4A1; the disease is breast cancer.