ACO2 and early-onset autosomal dominant Alzheimer disease: Apart from the immunological markers, bio functions performing a major role in inflammation could be observed, e.g., Alpha-synuclein, aconitase 2, enolase 1 and GADPH (glyceraldehyde-phosphate dehydrogenase), which acts in apoptotic processes and is also known to perform a role in Alzheimer’s disease.