NF1 and von Hippel-Lindau disease: Hereditary syndromes linked to PCCs and PGLs are von Hippel-Lindau disease (VHL), neurofibromatosis type 1 (NF-1), and multiple endocrine neoplasia, especially type 2 (MEN 2); however, a non-negligible number of PCCs and PGLs are non-functioning, and most of them are sporadic [3].