The common risk factors for the development of AD are increased age [4], family history [5], degeneration or vascular dysfunction [6], obesity [7], hypotension or hypertension [8], diabetes [9], hyperlipidemia [10], and the existence of epsilon 4 allele of the apolipoprotein E gene (ApoE4) [4]. The gene discussed is APOE; the disease is obesity due to melanocortin 4 receptor deficiency.