AKT1 and liver dysplastic nodule: From a molecular perspective, different cellular and inflammatory signaling pathways such as transforming growth factor-β (TGF-β), Phosphoinositide 3-kinase-protein kinase B (PI3K-Akt), Mitogen-activated protein kinase (MAPK) family including P38, extracellular signal-regulated kinases (ERK), Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), and c-Jun N-terminal kinases (JNKs) have been implied in DN pathogenesis [13,15].