INS and obesity due to melanocortin 4 receptor deficiency: In addition, children with T1D appeared to have a significantly higher rate of insulin use, DKA, and urine ketone incidences than those with T2D at admission time (26% vs. 0%, 26% vs. 0%, and 93.5% vs. 27.9%, respectively) in this study, whereas subjects with T2D presented with significantly higher levels of obesity and being overweight, as well as signs of insulin resistance (acanthosis nigricans) when compared to those with T1D (98.5% vs. 3.9% and 48.5% vs. 0%, respectively; Table 2).