TF and deep vein thrombosis: Another recent study showed that caspase-11 and gasdermin D activation are essential for LPS related thrombosis, demonstrating that gasdermin D increases procoagulant TF activity through phosphatidylserine externalization, a membrane phospholipid that favors TF decryption and also catalyzed the activation of coagulation proteins, which may also contribute to an increased thrombotic profile [20].