Thus, this gene may have important implications for neurodegenerative diseases, such as PD [52], and, as the D. melanogaster ortholog is also a choline transporter, this could explain the locomotor deficits observed by gene expression knockdown of Ctl1 (Figure 4), despite no other mutant phenotypic characteristics previously being described for Ctl1. This evidence concerns the gene SLC44A1 and neurodegenerative disease.