The knockdown of circ_0060745 inhibits the infiltration and migration of inflammatory cells and apoptosis of cardiomyocytes by modulating the deliverability of inflammatory cytokines, including IL-6, interleukin-12 (IL-12), IL-1β, TNF-α, and nuclear factor kappa B (NF-κB), in the myocardial fibroblasts after MI or under hypoxic conditions [65]. The gene discussed is NFKB1; the disease is myocardial infarction.