Interestingly, NUF2 expression was positively correlated with Th1 and Th2 cells but negatively correlated with DC cells and NK cells, suggesting that NUF2 may play two roles in tumor immune infiltration, a finding that was first reported in BRCA but has since been reported in other cancers [11,19,20,21]. The gene discussed is NUF2; the disease is neoplasm.