In the latest study, through the analysis of the TCGA database and the GEO database, it was found that NUF2 was upregulated in prostate cancer (PC) [11], non-small-cell lung cancer (NSCLC) [12], hepatocellular carcinoma (HCC) [13,14,15], esophageal squamous cell carcinoma (ESCC) [16], and kidney renal clear cell carcinoma (KIRC) [17] and was partially verified in patient tissue samples or cell lines. The gene discussed is NUF2; the disease is non-small cell lung carcinoma.