Furthermore, it was also shown that the AH concentrations of TGF-β-2 are increased in patients with POAG but are decreased in patients with PXF, while the levels of TGF-β-1 and TGF-β-3 are substantially elevated in the AH of PXF patients compared to those with other types of glaucoma [13,14,15,16]. The gene discussed is TGFB1; the disease is open-angle glaucoma.