FASLG and pulmonary arterial hypertension: Morrisroe et al. [99] tested 940 SSc patients for serum aPL, and demonstrated an association between anti-cardiolipin (aCL) IgG and PAH diagnosed via RHC, with higher titres corresponding to a higher likelihood of PAH (OR 4.60, 95% CI, 1.02–20.8).