Endometrial cancer-draining nodes had higher CD163 values (6.293 ± 6.842 vs. 2.682 ± 3.920, p = 0.0206) and lower CD8 values (10.341 ± 7.614 vs. 25 ± 11.019 p < 0.0001), compared to vulvar cancer-draining nodes. This evidence concerns the gene CD163 and endometrial cancer.