Moreover, some of the proteins identified in the present study have been associated with Hallmarks of Cancer specific proteins in breast cancer [34], including FINC, proteasome subunit alpha type-1 isoform 2 (PSA1), proteasome subunit alpha type-5 isoform 1 (PSA5), proteasome subunit beta type-3 (PSB3), phosphoglycerate kinase 1 (PGK1), heat shock cognate 71 kDa protein isoform 1 (HSP7C) and glutathione S-transferase p (GSTP1) which may provide insights into the early detection of breast disease. This evidence concerns the gene PGK1 and breast disorder.