Labbozzetta et al. [46] show that in a study conducted in the AML MDR cell line, HL-60R, which is derived from HL-60 cells by selecting for doxorubicin resistance, phytol produces a strong decrease in the expression of P-gp at 25 μg/mL (84 μM), at both the mRNA and protein levels. This evidence concerns the gene PGP and acute myeloid leukemia.