The genomic region of interest on chromosome 1 between base pairs 23,920,590 and 25,516,845 includes 287 single nucleotide polymorphisms (SNPs), of which 63 neighboring SNPs mapped to CNR2 revealed statistically significant [p < 0.05 (log(10) < −1.3] associations with colon cancer. The gene discussed is CNR2; the disease is malignant colon neoplasm.