IL-5 is mainly produced by T helper-2 (Th2) lymphocytes, mainly involved in the response to parasites and allergies, and group 2 innate lymphoid cells (ILC2), and its expression is regulated by several transcription factors, such as GATA3 (BioCarta GATA3 pathway (p-value = 0.009, FDR = 0.099) [46,47]. The gene discussed is GATA3; the disease is allergic disease.