Finally, at the bottom of this figure, are the top five diseases with the best ratings of statistical significance for the contribution of FCGR2B to their pathogenesis, namely: acute myeloid leukemia (PADJ < 10−84), rheumatoid arthritis (PADJ < 10−71), inflammation (PADJ < 10−69), systemic lupus erythematosus (PADJ < 10−67), and autoimmune diseases (PADJ < 10−60). This evidence concerns the gene FCGR2B and systemic lupus erythematosus.