PBRM1 and nonpapillary renal cell carcinoma: The most commonly altered genes in this cohort were VHL (n = 24, 57.1%), PBRM1 (n = 14, 33.3%), SETD2 (n = 11, 26.2%), and BAP1 (n = 11, 26.2%), which are generally similar to those previously reported for ccRCC (Figure S2) [12,13].