Among the 32 tumour entities investigated, strong CALCRL expression was present in all types of thyroid carcinomas, as well as parathyroid adenomas, small-cell lung cancers, large cell neuroendocrine carcinomas of the lung, pancreatic neuroendocrine neoplasms, renal clear cell carcinomas, pheochromocytomas, lymphomas, and melanomas. This evidence concerns the gene CALCRL and clear cell renal carcinoma.