Among the tumour types investigated in this study, CALCRL was predominantly expressed in all types of thyroid carcinomas, as well as parathyroid adenomas, small-cell lung cancers, large cell neuroendocrine carcinomas of the lung, pancreatic neuroendocrine neoplasms, renal clear cell carcinomas, pheochromocytomas, lymphomas, and melanomas. The gene discussed is CALCRL; the disease is hereditary pheochromocytoma-paraganglioma.