TGFB1 and cancer: Their crosstalk with cancer cells is mediated with a complex signaling network that consists of signaling pathways for transforming growth factor-beta (TGF-β), mitogen-activated protein kinase (MAPK), Wnt/β-catenin, Janus kinase/signal transducers and activators of transcription (JAK/STATs), epidermal growth factor receptor (EGFR), nuclear factor-light kappa-enhancer of activated B cells (NF-κB), etc. [20,21,22].