OXTR and psychiatric disorder: However, we propose that the ostensible paradox of contradictory results obtained by various research groups might be explained in such a way that similar variabilities in OXTR polymorphisms or DNA methylation may occur in both patients suffering from different diseases (especially mental disorders) and healthy controls; however, the effects of specific SNPs or levels of methylation can be significantly more pronounced in affected persons due to their influence on ongoing pathological processes and enhancement of symptoms.