A functional interaction between the dopaminergic (DAergic) system and the ECS due to the coexpression of Cnr1 and dopamine D2 receptors (Drd2) genes [15] and to their signal transduction convergence [16] has been suggested both at the level of the prefrontal cortex (PFC) and in several limbic structures as possible neuroanatomical loci for neurodevelopmental disorders [11]. The gene discussed is DRD2; the disease is neurodevelopmental disorder.