IL10 and periodontitis: In porphyromonas-gingivalis-infected lean and obese experimental periodontitis mice, alive and pasteurized Akk or Amuc_1100 all significantly prevented porphyromonas-gingivalis-induced periodontal destruction and inflammatory infiltration while inhibiting TNF-α levels and increasing IL-10 production, which was further confirmed in porphyromonas-gingivalis-infected macrophages [115].