Treatment with obtustatin, a KTS disintegrin, a specific inhibitor of α1β1, reduced the movement of triple-negative breast cancer cells inoculated on a V-type collagen matrix [20] and reduced the migration and invasion of neuroblastoma cells with high TRPM2 expression [21], indicating the potential of α1β1 to increase cancer cell metastasis. This evidence concerns the gene TRPM2 and neuroblastoma.