Annexin V-TRAIL (TP8), a fusion protein composed of ANV and tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL), effectively inhibited tumor growth in mouse xenografts from multiple cancer cell types, including non-small-cell lung cancer (A549), colon cancer (Colo205), and liver cancer (Bel7402) [32]. This evidence concerns the gene ANXA5 and colonic neoplasm.