CLEC2D and acute lymphoblastic leukemia: LLT1 expression in CD3+ T cells of ALL subjects at diagnosis (day 0) showed a median fluorescence intensity ratio (MFIR) value of 2.24 as compared to 2.74 in healthy individuals, which further decreased to 1.68 after induction chemotherapy treatment (p = 0.0247), as shown in Figure 4a.