The eight unrelated families that exhibited RP were found to harbor seven different RPGR variants: c.1217dupT p.(Ser407Ilefs*46), c.2236_2237delGA p.(Glu746Argfs*23), c.G1978G>A p.(Glu660*), c.457G>A p.(Ala153Thr), c.1506+1G>T, c.2340_2341delAG p.(Arg780Serfs*54), and c.1245+704_1415-2286del (ex-11del); the last of these was found in two families. This evidence concerns the gene RPGR and retinitis pigmentosa 1.